Welcome to our Downstream Processing Library.

This library contains citations for our publications in the field of downstream processing. Copyright restrictions preclude us from providing electronic copies for some entries, but you are welcome to download any linked files for your individual personal used. Entries are posted in reverse chronological order in each section. There is a lot of new material and we’ll be updating content regularly so feel free to visit as often as you like. New entries are prepared in Acrobat 7. If you need to update your copy of Acrobat Reader, you can download a free copy from http://www.adobe.com/.

If you wish to use any of these files in support of a report or publication, you can cite the web address in place of the journal. The addresses for even the earliest files have remained unchanged since they were first posted, so you can be confident that readers and editors will be able to find them.

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Posters

Gagnon, P., Rodriquez, G., Zaidi, S., Preliminary Results Towards Development of a Simple Rapid Method for Dissociation and Fractionation of Heavy and Light Chain from Monoclonal IgG, Poster, 4th International Monolith Symposium, Portoroz, Slovenia, May 29 - June 2, 2010

Gagnon, P., Cheung, C-W., Yazaki, P., 2009, Multimodal Interactions of IgG, Fab, F(ab)2, Fc, and Aggregates with Hydroxyapatite, Poster, 22nd International IBC Antibody Development and Production, Carlsbad, CA, March 4-6

A high speed monolithic assay for IgM quantitation in cell culture produiction and purification process monitoring, Pete Gagnon, Richard Richieri, Simin Zaidi, Roy Sevilla, Alexander Brinkman, Third Wilbio Conference on Purification of Biological Products, September 24-26, Waltham, MA USA.

A comparison of microparticulate, membrane, and monolithic anion exchangers for polishing applications in the purification of IgG monoclonal antibodies, Pete Gagnon, Richard Richieri, Simin Zaidi, Franics Aolin, IBC International Conference and Exposition, October 1-4, Boston, MA, USA

Buffers and conditions for use and maintenance of ceramic hydroxyapatite, Julia Zhen, Pete Gagnon, Mark Snyder, 18th International IBC Conference on Antibody Development and Production, La Costa Spa and Resort, Carlsbad, CA, Feb 28 - Mar 2, 2007.

Hydroxyapatite as a Capture Method for Purification of Monoclonal Antibodies, P. Gagnon, S. Zaidi, and S. Summers, IBC World Conference and Exposition, San Francisco, Nov. 6-9, 2006. Awarded Best Poster, Recovery and Purification.

The effect of different Hofmeister ions on aggregate removal by hydroxyapatite 232nd Meeting of the American Chemical Society, San Francisco, 9/13/06

P. Ng, C. Aberin, J. He, H. Mekosh, J. Zhen and P. Gagnon, 2006, A 3-mechanism model for adsorption of IgG on CHT ceramic hydroxyapatite, Prep 2006, May 14-17, Baltimore, MD. Posted courtesy of Bio-Rad Laboratories.

P. Ng, N. Liu, C. Eller, S. Farashchi, H. Chen, A. Paulus and P. Gagnon, 2005, Application of CHT™ Ceramic Hydroxyapatite for Proteomic Analysis, ISPPP: 25th International Symposium on the Separation of Proteins, Peptides, and Polynucleotides. Nov. 6-9, St. Petersburg, FL. Posted courtesy of Bio-Rad Laboratories.

P. Ng, P. Gagnon and C. Aberin, 2005, Differential retention of DNA on ceramic hydroxyapatite and ceramic fluorapatite, Prep 2005 May 2-6, Philadelphia, PA. Posted courtesy of Bio-Rad Laboratories.

P. Gagnon, T. Mayes, and A. Danielsson, 1997, An adaptation of hydrophobic interaction chromatography for estimation of protein solubility optima, First Annual Conference on the Analysis of Well Characterized Biological Products, San Francisco

P. Gagnon, B. Godfrey and D. Ladd, 1995, A method for obtaining unique selectivities in ion exchange chromatography by addition of organic solvents to the mobile phase, 15th International Symposium on HPLC of Proteins, Peptides, and Polynucleotides, Boston

P. Gagnon and E. Grund, 1995, Obtaining useful capacity determinations in hydrophobic interaction chromatography, 15th International Symposium on HPLC of Proteins, Peptides, and Polynucleotides, Boston



P. Gagnon, C. Schmidt, and G. Sofer, 1995, Developing sample application conditions for large scale ion exchange chromatography, IBC Conference on Monoclonal Antibody Purification, San Francisco

P. Gagnon and E. Grund, 1995, Selecting hydrophobic interaction media for antibody purification, IBC Conference on Monoclonal Antibody Purification, San Francisco

P. Gagnon, T. Lindbäck, and E. Grund, 1993, Systematic development of conditions for preparative sample application with hydrophobic interaction chromatography, 13th International Sympo-sium on HPLC of Proteins, Peptides, and Polynucleotides, San Francisco

P. Gagnon, 1992, Multiple mechanisms for improving binding of IgG to Protein A, BioEast '92, Washington, D.C.

P. Gagnon, R. Eksteen, J. Maikner, and P. Cartier, 1991, Purification of monoclonal antibodies by high performance ion exchange and hydrophobic interaction chromatography, BioEast ‘91, Washington D.C.

P. Gagnon, M. Kraus, J. Maikner, and P. Cartier, 1990, Purification process development and scale-up of monoclonal antibodies, Analytica, Munich

P. Gagnon, R. Eksteen, P. Cartier, and J. Maikner, 1989, Method development and scale-up in the purification of monoclonal antibodies, American Society of Microbiology, Anaheim

P. Gagnon, J. Henner, S. Szathmary, P. Grandics, and T. Bekele, 1988, Development of novel hydrophobic interaction chromatography media for the purification of therapeutic proteins, The Engineering Conferences Meeting on Bioprocessing, Kailua-Kona

P. Gagnon, J. Henner, P. Grandics, and S. Szathmary, 1988, Novel hydrophobic interaction chromatography media for the purification of therapeutic proteins, Meeting of the American Chemical Society, Los Angeles.

P. Gagnon and B. Price, 1987, Industrial Scale Purification of Monoclonal Antibodies, 4th Biotechnology and Hybridoma Conference, San Francisco

P. Gagnon, D. Barantes, and A. Goodridge, 1983, Preferential orientation of experimentally modified proteins on a high performance cation exchanger, 3rd International Symposium on HPLC of Proteins, Peptides, and Polynucleotides, Baltimore[Articles] [Presentations] [Posters] [Newsletters] [Books